Review




Structured Review

Affinity Biosciences ang ii af5124
Effect of POH on the protein expression of the ACE-AngII-AT1R and ACE2-Ang-(1–7)-MAS axis in HPH rats. ( a , c , e , g , i , j ) Representative western blotting bands and quantification of ACE, AngII, AT1R and Mas proteins. ( b , d , f , h , k ) Concentration of AngII, ACE, AT1R and Ang 1–7 in RV tissues detected by ELISA kits. Data are presented as the mean ± SD. AngII: Angiotensin II. ACE: Angiotensin-Converting Enzyme. AT1R: <t>Angiotensin</t> <t>II</t> Type 1 Receptor. ACE2: angiotensin-converting enzyme 2. Ang-(1–7): angiotensin-(1–7). Data are presented as the mean ± SD. ACE: angiotensin-convertingenzyme, AngII: angiotensin II, AT1R: AngII type 1 receptor. <t>Ang</t> <t>II</t> (protein): Decreasing, P > 0.05, R 2 = 0.173, no dose–effect relationship. Ang II (concentration): Decreasing, P > 0.05, R 2 = 0.241, no dose–effect relationship. ACE (concentration): Increasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (concentration): Decreasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (protein): Increasing, P > 0.05, R 2 = 0.216, no dose–effect relationship. Ang1-7: Decreasing, P < 0.05, R 2 = 0.523, no dose–effect relationship. ( # P < 0.05 vs . control group, * P < 0.05, vs . hypoxia group, a P < 0.05, vs . Hyp + sildenafil group, b P < 0.05, vs . Hyp + POH25mg/kg/d, c P < 0.05, vs . Hyp + POH50mg/kg/d).
Ang Ii Af5124, supplied by Affinity Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ang+ii+af5124/anti+collagen+i/pmc12887052-61-0-11
Average 86 stars, based on 1 article reviews
ang ii af5124 - by Bioz Stars, 2026-10
86/100 stars

Images

1) Product Images from "Perillyl alcohol attenuates hypoxia induced right ventricular dysfunction and remodeling by balancing the renin angiotensin aldosterone system in rats"

Article Title: Perillyl alcohol attenuates hypoxia induced right ventricular dysfunction and remodeling by balancing the renin angiotensin aldosterone system in rats

Journal: Scientific Reports

doi: 10.1038/s41598-025-34539-6

Effect of POH on the protein expression of the ACE-AngII-AT1R and ACE2-Ang-(1–7)-MAS axis in HPH rats. ( a , c , e , g , i , j ) Representative western blotting bands and quantification of ACE, AngII, AT1R and Mas proteins. ( b , d , f , h , k ) Concentration of AngII, ACE, AT1R and Ang 1–7 in RV tissues detected by ELISA kits. Data are presented as the mean ± SD. AngII: Angiotensin II. ACE: Angiotensin-Converting Enzyme. AT1R: Angiotensin II Type 1 Receptor. ACE2: angiotensin-converting enzyme 2. Ang-(1–7): angiotensin-(1–7). Data are presented as the mean ± SD. ACE: angiotensin-convertingenzyme, AngII: angiotensin II, AT1R: AngII type 1 receptor. Ang II (protein): Decreasing, P > 0.05, R 2 = 0.173, no dose–effect relationship. Ang II (concentration): Decreasing, P > 0.05, R 2 = 0.241, no dose–effect relationship. ACE (concentration): Increasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (concentration): Decreasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (protein): Increasing, P > 0.05, R 2 = 0.216, no dose–effect relationship. Ang1-7: Decreasing, P < 0.05, R 2 = 0.523, no dose–effect relationship. ( # P < 0.05 vs . control group, * P < 0.05, vs . hypoxia group, a P < 0.05, vs . Hyp + sildenafil group, b P < 0.05, vs . Hyp + POH25mg/kg/d, c P < 0.05, vs . Hyp + POH50mg/kg/d).
Figure Legend Snippet: Effect of POH on the protein expression of the ACE-AngII-AT1R and ACE2-Ang-(1–7)-MAS axis in HPH rats. ( a , c , e , g , i , j ) Representative western blotting bands and quantification of ACE, AngII, AT1R and Mas proteins. ( b , d , f , h , k ) Concentration of AngII, ACE, AT1R and Ang 1–7 in RV tissues detected by ELISA kits. Data are presented as the mean ± SD. AngII: Angiotensin II. ACE: Angiotensin-Converting Enzyme. AT1R: Angiotensin II Type 1 Receptor. ACE2: angiotensin-converting enzyme 2. Ang-(1–7): angiotensin-(1–7). Data are presented as the mean ± SD. ACE: angiotensin-convertingenzyme, AngII: angiotensin II, AT1R: AngII type 1 receptor. Ang II (protein): Decreasing, P > 0.05, R 2 = 0.173, no dose–effect relationship. Ang II (concentration): Decreasing, P > 0.05, R 2 = 0.241, no dose–effect relationship. ACE (concentration): Increasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (concentration): Decreasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (protein): Increasing, P > 0.05, R 2 = 0.216, no dose–effect relationship. Ang1-7: Decreasing, P < 0.05, R 2 = 0.523, no dose–effect relationship. ( # P < 0.05 vs . control group, * P < 0.05, vs . hypoxia group, a P < 0.05, vs . Hyp + sildenafil group, b P < 0.05, vs . Hyp + POH25mg/kg/d, c P < 0.05, vs . Hyp + POH50mg/kg/d).

Techniques Used: Expressing, Western Blot, Concentration Assay, Enzyme-linked Immunosorbent Assay, Control



Similar Products

86
Affinity Biosciences ang ii af5124
Effect of POH on the protein expression of the ACE-AngII-AT1R and ACE2-Ang-(1–7)-MAS axis in HPH rats. ( a , c , e , g , i , j ) Representative western blotting bands and quantification of ACE, AngII, AT1R and Mas proteins. ( b , d , f , h , k ) Concentration of AngII, ACE, AT1R and Ang 1–7 in RV tissues detected by ELISA kits. Data are presented as the mean ± SD. AngII: Angiotensin II. ACE: Angiotensin-Converting Enzyme. AT1R: <t>Angiotensin</t> <t>II</t> Type 1 Receptor. ACE2: angiotensin-converting enzyme 2. Ang-(1–7): angiotensin-(1–7). Data are presented as the mean ± SD. ACE: angiotensin-convertingenzyme, AngII: angiotensin II, AT1R: AngII type 1 receptor. <t>Ang</t> <t>II</t> (protein): Decreasing, P > 0.05, R 2 = 0.173, no dose–effect relationship. Ang II (concentration): Decreasing, P > 0.05, R 2 = 0.241, no dose–effect relationship. ACE (concentration): Increasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (concentration): Decreasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (protein): Increasing, P > 0.05, R 2 = 0.216, no dose–effect relationship. Ang1-7: Decreasing, P < 0.05, R 2 = 0.523, no dose–effect relationship. ( # P < 0.05 vs . control group, * P < 0.05, vs . hypoxia group, a P < 0.05, vs . Hyp + sildenafil group, b P < 0.05, vs . Hyp + POH25mg/kg/d, c P < 0.05, vs . Hyp + POH50mg/kg/d).
Ang Ii Af5124, supplied by Affinity Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ang+ii+af5124/anti+collagen+i/pmc12887052-61-0-11
Average 86 stars, based on 1 article reviews
ang ii af5124 - by Bioz Stars, 2026-10
86/100 stars
  Buy from Supplier

90
Affinity Biosciences rabbit anti-rat ang ii monoclonal antibody af5124
Effect of POH on the protein expression of the ACE-AngII-AT1R and ACE2-Ang-(1–7)-MAS axis in HPH rats. ( a , c , e , g , i , j ) Representative western blotting bands and quantification of ACE, AngII, AT1R and Mas proteins. ( b , d , f , h , k ) Concentration of AngII, ACE, AT1R and Ang 1–7 in RV tissues detected by ELISA kits. Data are presented as the mean ± SD. AngII: Angiotensin II. ACE: Angiotensin-Converting Enzyme. AT1R: <t>Angiotensin</t> <t>II</t> Type 1 Receptor. ACE2: angiotensin-converting enzyme 2. Ang-(1–7): angiotensin-(1–7). Data are presented as the mean ± SD. ACE: angiotensin-convertingenzyme, AngII: angiotensin II, AT1R: AngII type 1 receptor. <t>Ang</t> <t>II</t> (protein): Decreasing, P > 0.05, R 2 = 0.173, no dose–effect relationship. Ang II (concentration): Decreasing, P > 0.05, R 2 = 0.241, no dose–effect relationship. ACE (concentration): Increasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (concentration): Decreasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (protein): Increasing, P > 0.05, R 2 = 0.216, no dose–effect relationship. Ang1-7: Decreasing, P < 0.05, R 2 = 0.523, no dose–effect relationship. ( # P < 0.05 vs . control group, * P < 0.05, vs . hypoxia group, a P < 0.05, vs . Hyp + sildenafil group, b P < 0.05, vs . Hyp + POH25mg/kg/d, c P < 0.05, vs . Hyp + POH50mg/kg/d).
Rabbit Anti Rat Ang Ii Monoclonal Antibody Af5124, supplied by Affinity Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ang+ii+af5124/rabbit+anti+rat+ang+ii+monoclonal+antibody+af5124/pm34921827-105-20-26
Average 90 stars, based on 1 article reviews
rabbit anti-rat ang ii monoclonal antibody af5124 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


Effect of POH on the protein expression of the ACE-AngII-AT1R and ACE2-Ang-(1–7)-MAS axis in HPH rats. ( a , c , e , g , i , j ) Representative western blotting bands and quantification of ACE, AngII, AT1R and Mas proteins. ( b , d , f , h , k ) Concentration of AngII, ACE, AT1R and Ang 1–7 in RV tissues detected by ELISA kits. Data are presented as the mean ± SD. AngII: Angiotensin II. ACE: Angiotensin-Converting Enzyme. AT1R: Angiotensin II Type 1 Receptor. ACE2: angiotensin-converting enzyme 2. Ang-(1–7): angiotensin-(1–7). Data are presented as the mean ± SD. ACE: angiotensin-convertingenzyme, AngII: angiotensin II, AT1R: AngII type 1 receptor. Ang II (protein): Decreasing, P > 0.05, R 2 = 0.173, no dose–effect relationship. Ang II (concentration): Decreasing, P > 0.05, R 2 = 0.241, no dose–effect relationship. ACE (concentration): Increasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (concentration): Decreasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (protein): Increasing, P > 0.05, R 2 = 0.216, no dose–effect relationship. Ang1-7: Decreasing, P < 0.05, R 2 = 0.523, no dose–effect relationship. ( # P < 0.05 vs . control group, * P < 0.05, vs . hypoxia group, a P < 0.05, vs . Hyp + sildenafil group, b P < 0.05, vs . Hyp + POH25mg/kg/d, c P < 0.05, vs . Hyp + POH50mg/kg/d).

Journal: Scientific Reports

Article Title: Perillyl alcohol attenuates hypoxia induced right ventricular dysfunction and remodeling by balancing the renin angiotensin aldosterone system in rats

doi: 10.1038/s41598-025-34539-6

Figure Lengend Snippet: Effect of POH on the protein expression of the ACE-AngII-AT1R and ACE2-Ang-(1–7)-MAS axis in HPH rats. ( a , c , e , g , i , j ) Representative western blotting bands and quantification of ACE, AngII, AT1R and Mas proteins. ( b , d , f , h , k ) Concentration of AngII, ACE, AT1R and Ang 1–7 in RV tissues detected by ELISA kits. Data are presented as the mean ± SD. AngII: Angiotensin II. ACE: Angiotensin-Converting Enzyme. AT1R: Angiotensin II Type 1 Receptor. ACE2: angiotensin-converting enzyme 2. Ang-(1–7): angiotensin-(1–7). Data are presented as the mean ± SD. ACE: angiotensin-convertingenzyme, AngII: angiotensin II, AT1R: AngII type 1 receptor. Ang II (protein): Decreasing, P > 0.05, R 2 = 0.173, no dose–effect relationship. Ang II (concentration): Decreasing, P > 0.05, R 2 = 0.241, no dose–effect relationship. ACE (concentration): Increasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (concentration): Decreasing, P < 0.05, R 2 = 0.426, no dose–effect relationship. ACE2 (protein): Increasing, P > 0.05, R 2 = 0.216, no dose–effect relationship. Ang1-7: Decreasing, P < 0.05, R 2 = 0.523, no dose–effect relationship. ( # P < 0.05 vs . control group, * P < 0.05, vs . hypoxia group, a P < 0.05, vs . Hyp + sildenafil group, b P < 0.05, vs . Hyp + POH25mg/kg/d, c P < 0.05, vs . Hyp + POH50mg/kg/d).

Article Snippet: Ang II (AF5124) and collagen III antibodies (AF5457) were obtained from Affbiotech, Jiangsu, China.

Techniques: Expressing, Western Blot, Concentration Assay, Enzyme-linked Immunosorbent Assay, Control